Background. Traditional Chinese medicine (TCM) has long been used to treat chronic atrophic gastritis (CAG). The aim of the\npresent study was to evaluate the TCMsyndrome characteristics of CAG and its core pathogenesis so as to promote optimization of\ntreatment strategies. Methods. This study was based on a participant survey conducted in 4 hospitals in China. Patients diagnosed\nwith CAG were recruited by simple random sampling. Exploratory factor analysis (EFA) was conducted on syndrome extraction.\nResults. Common factors extracted were assigned to six syndrome patterns: qi deficiency, qi stagnation, blood stasis, phlegm\nturbidity, heat, and yang deficiency. Distribution frequency of all syndrome patterns showed that qi deficiency, qi stagnation, blood\nstasis, phlegm turbidity, and heat excess were higher (76.7%ââ?¬â??84.2%) compared with yang deficiency (42.5%). Distribution of main\nsyndrome patterns showed that frequencies of qi deficiency, qi stagnation, phlegm turbidity, heat, and yang deficiency were higher\n(15.8%ââ?¬â??20.8%) compared with blood stasis (8.3%). Conclusions.The core pathogenesis of CAG is combination of qi deficiency, qi\nstagnation, blood stasis, phlegm turbidity, heat, and yang deficiency. Therefore, treatment strategy of herbal prescriptions for CAG\nshould include herbs that regulate qi, activate blood, resolve turbidity, clear heat, remove toxin, and warm yang.
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